The mechanisms underlying intellectual disabilities or autism remain largely unknown. Researchers in the labs of Prof. Pierre Vanderhaeghen and Prof. Vincent Bonin at the VIB-KU Leuven Center for ...

An international research team has provided an unprecedented look at how gene regulation evolves during human brain development, showing how the 3D structure of chromatin—DNA and proteins—plays a ...

Previous research has found that the human brain reaches maturity sometime in the 20s, but a new study suggests that it never stops developing. Neuroscientists at the University of Cambridge have ...

In a bid to better understand, and potentially treat, a host of conditions that affect early cognition, neurodevelopment, and the brain later in life, investigators at Johns Hopkins Medicine and ...

The human brain undergoes significant development during the final prenatal months and through the first year of life. And while scientists have begun to map the developmental trajectories of this ...

Human brain morphology undergoes complex changes over the lifespan. Despite recent progress in tracking brain development via normative models, current knowledge of underlying biological mechanisms is ...

A new study has created a map of DNA modification in two regions of the brain critical to learning, memory and emotional regulation. The map offers a benchmark for ensuring stem cell-based models ...

Hundreds of genes have been linked to autism, yet the precise molecular and cellular mechanisms behind it remain largely unclear. A new study published in Nature, led by Gaia Novarino at the Institute ...

The perinatal period, encompassing both prenatal and early postnatal stages, is a highly dynamic and foundational phase of brain development. Despite its significance, limited work has tracked brain ...

Researchers have now discovered that HAR123, a regulatory gene sequence, is an important factor in human brain development. Even though humans are closely related to chimps, the slight differences in ...

Just a few weeks after conception, stem cells are already orchestrating the future structure of the human brain. A new Yale-led study shows that, early in development, molecular “traffic cops” known ...

What unique processes conspire to create a healthy, functional human brain? How can we be so genetically similar to, say, chimpanzees, and yet be light-years more sophisticated cognitively and ...