A new CRISPR approach can control genes without cutting DNA, opening a safer path for treating genetic diseases. A newly ...

Sickle cell disease (SCD) is a group of genetic blood disorders. A person inherits SCD from their parents when they inherit two copies of the sickle cell gene, one from each parent. This hereditary ...

Scientists from Johns Hopkins Medicine and eight other institutions in the United States, Africa and Europe say they have identified a potential new gene target that could be edited to treat sickle ...

When Dr. Ambroise Wonkam walked into a panel on medical genetics out of curiosity, he had no idea it would shape the course of his career. Born in Cameroon, Wonkam has dedicated his career to studying ...

Researchers have found that being a carrier for sickle cell disease, known as having sickle cell trait, increases the risk of blood clots, a risk that is the same among diverse human populations that ...

UCSF Benioff Children’s Hospital Oakland is enrolling patients in an innovative clinical trial that seeks to cure sickle cell disease. The trial is the first in the U.S. to apply non-viral CRISPR-Cas9 ...

Sickle cell disease refers to a group of genetic diseases that impact a protein that ferries oxygen through the blood. That protein is called hemoglobin, and in sickle cell disease, aberrant ...

People are often encouraged to “know their status,” however this healthy habit can be applied to more than just safe-sex practices. Although they are not the only community who suffers with sickle ...

A new generation of CRISPR technology developed at UNSW Sydney offers a safer path to treating genetic diseases like sickle cell, while also proving beyond doubt that chemical tags on DNA—often ...

Cristina Pina receives funding from Children's Cancer and Leukaemia Group via the Little Princess Trust and the National Centre for the Replacement, Reduction and Refinement of Animals in Research.

Genetic disorders can occur due to mutations in one gene (monogenic), multiple genes (multifactorial inheritance), and mutation in one or more chromosomes. Point mutations are where one nucleotide in ...

National Institutes of Health (NIH) researchers and collaborators have found that being a carrier for sickle cell disease, known as having sickle cell trait, increases the risk of blood clots, a risk ...