Turning genes on and off is like flipping a light switch, controlling whether genes in a cell are active. When a gene is ...

Modified ChIP-seq and 4C-seq approaches, using urea-purified crosslinked chromatin, uncovered a two-tiered chromatin organization mediated by SATB1 that is linked to gene expression.

Most people recognize Alzheimer's from its devastating symptoms such as memory loss, while new drugs target pathological aspects of disease manifestations, such as plaques of amyloid proteins. Now a ...