Taste, pain, or response to stress -- nearly all essential functions in the human body are regulated by molecular switches called G protein-coupled receptors (GPCRs). Researchers have uncovered the ...
The discovery of G protein-coupled receptor (GPCR) heteromers has revealed a new level of complexity in their functional characteristics. This review explores a variety of methodologies and live cell ...
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Structural findings reveal how distinct GPCR ligands create different levels of activation
G-protein coupled receptors (GPCRs) are proteins triggered by ligands (protein-binding chemicals) from outside cells to transmit signals inside the cell. These signals are transmitted primarily ...
Opioid receptors are fantastic targets for treating pain—but unfortunately, the drugs that target them can be addictive. Because the molecules suppress breathing and heart function, those drugs can ...
G protein-coupled receptors (GPCRs) are expressed on the surface of cells and regulate a range of important functions. Because they are involved in so many sensory and physiological processes, ...
A GPS-like technique has been used to track G protein-coupled receptor movement, revealing how these essential receptors function. Although G protein-coupled receptors (GPCRs) are crucial to the ...
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