In the realm of biological sciences, bile acids stand as pivotal molecules, playing a multifaceted role in various physiological processes within organisms. Bile acids are specialized molecules ...

Hepatic synthesis of bile acids is the primary pathway for cholesterol catabolism. The cholesterol 7α-hydroxylase enzyme (encoded by CYP7A1) represents the rate-limiting step of the multi-enzymatic ...

The gall bladder is seldom brought up in conversation until it is out of order. This little, pear-shaped organ lies just under the liver and is the ma.

The discovery of dedicated bile acid receptors and further research defined multiple bile acid signalling routes affecting bile acid synthesis, lipid synthesis, gluconeogenesis, inflammation, liver ...

There are many digestive juices present in our body that helps to improve digestive functions. Bile juice is one of the major components that plays role in this problem. Bile is basically a yellowish ...

Examining gut health from a different angle, Flinders University’s Associate Professor Robyn Meech is looking at what can trigger colon cancer – and she believes bile acids may provide a significant ...

A new study presented today at the International Liver Congress™ 2012 demonstrates that the gut microbiota has a profound systemic effect on bile acid metabolism.(1) Bile acids are synthesised from ...

The gut microbiota have a known role in modulating gut immune homeostasis. Largely, through the development and function of host immune cells, including T helper cells expressing interleukin-17A. It ...

The care of patients with cholestatic liver diseases such as primary sclerosing cholangitis (PSC) is challenging, partly due ...

Researchers have identified a new axis of host defense by studying what happens during enteric infection -- a term that encompasses all types of intestinal infections including so called 'stomach flu.

Researchers have identified a new axis of host defense by studying what happens during enteric infection—a term that encompasses all types of intestinal infections including so called “stomach flu.” A ...

Bile duct cancer, also known as cholangiocarcinoma, is a rare form of cancer that affects the bile ducts. Two bile ducts in the human body connect the liver and gallbladder to the small intestine.