This is a preview. Log in through your library . Abstract We used fracture-label to establish ultra-structural localization of glycoproteins in cross-fractured nuclei of duodenal columnar and exocrine ...

The protein complex responsible for the distribution of chromosomes during cell division is assembled in the transition regions between heterochromatin and euchromatin. The centromere is a specialized ...

In their paper the team discusses their novel view of euchromatin in the cell and shows how the revealed organization is relevant to genome functions. “Our ultimate goal is to reveal how genomic ...

A eukaryotic chromosome relies on the function of multiple spatially distributed DNA replication origins for its stable inheritance. The spatial location of an origin is determined by the chromosomal ...

New research uncovers leading mechanisms of separation of active from inactive fractions of the genome in the cell nucleus and turns our picture of the nucleus upside down. Spatial separation of ...

This press release is available in German. To fit the two-meter long DNA molecule into a cell nucleus that is only a few thousandths of a millimetre in size, long sections of the DNA must be strongly ...

A recent study In Press at the Journal of Cell Biology reports that herpes simplex virus 1 (HSV-1) exploits heterochromatin to successfully exit the nucleus. The heterochromatin markers macroH2A1 and ...

Epigenetics is the study of inherited phenotypic changes caused by mechanisms other than mutations in the underlying DNA sequence. In mammalian cells, most of the chromatin—a complex of DNA, proteins, ...