Megestrol, which helps treat hot flashes associated with menopause, may have the added benefit of slowing the growth of ...

A drug mimicking the hormone progesterone has anti-cancer activity when used together with conventional anti-estrogen ...

A drug mimicking the hormone progesterone has anti-cancer activity when used together with conventional anti-estrogen ...

The evERA breast cancer trial marks a turning point for some patients with a specific type of advanced breast cancer known as ...

At the San Antonio Breast Cancer Symposium (SABCS), investigators outlined the rationale and design of the ERADICATE, a first ...

Low-dose megestrol enhances hormone therapy for ER-positive breast cancer, reducing tumor proliferation and improving ...

Hormone therapies have played a major role in improving survival for patients with ER+ breast cancer [1]. By blocking or reducing estrogen’s impact, these treatments slow the cancer’s growth and help ...

Many breast cancer drugs block estrogen receptors inside cancer cells. Blocking the receptors early in disease progression staves off metastasis. But most patients with advanced disease eventually ...

STRIvE-02: A First-in-Human Phase I Study of Systemically Administered B7-H3 Chimeric Antigen Receptor T Cells for Patients With Relapsed/Refractory Solid Tumors Overall, 262 patients with ER+/HER2– ...

The modulation of colorectal cancer (CRC) by oestrogen receptors has emerged as a field of great promise, drawing attention to the differential roles of receptor subtypes in tumour initiation, ...

Estrogen-dependent cancers are cancers that grow in response to the hormone estrogen. These include certain types of breast cancer, uterine cancer, and ovarian cancer. In these cancers, estrogen can ...