MAPK signaling works like a molecular switchboard inside epithelial cells, turning outside stress into gene-level commands. IL-33 is an alarm signal cytokine that normally stays tucked inside ...

ACT: Activation-induced T-cell derived and chemokine related; BCA: B cell-attracting chemokine; BLC: B-lymphocyte chemoattractant; BRAK: Breast and kidney-expressed chemokine; CTACK: Cutaneous ...

Chinese scientists have discovered a common mechanism by which structurally distinct proteins elicit an allergic reaction, showing they cause the formation of pores in epithelial airway cells. That ...

Study data indicate that membrane perforation registers as danger and is sufficient to launch type 2 immune pathways in the airway epithelium. The authors argue that many otherwise unrelated allergens ...