When combined, the effects of mutations in different genes often deviate from what would be expected by looking at them separately. Researchers at the University of València in Spain have shown that ...

Why evolutionary genetics does not always add up / Edmund D. Brodie III -- Beyond the average : the evolutionary importance of gene interactions and variability of epistatic effects / Patrick C.

Experiments reveal that a time-dependent epistatic interaction influences how mice respond to opioids, and that intracellular fibroblast growth factors also influence opioid sensitivity.

Researchers are presenting a novel concept for the mathematical modeling of genetic interactions in biological systems. The team has successfully identified master regulators within the context of an ...