Given how profound an influence opioids have on the world – for better or worse – scientists know surprisingly little about how these drugs actually work. A recent study led by researchers from ...
DOPr endocytosis and endosomal signaling by protein kinase C (PKC) and extracellular signal-regulated kinase (ERK) pathways mediated the sustained inhibitory actions of endogenous opioids and DOPr ...
For decades, opioids have been the blunt instrument of modern pain care, powerful enough to quiet severe suffering yet risky ...
New research undertaken by American and Chinese researchers may pave the way for safer opioid painkillers, thanks to the use of cryo-electron microscopy (cryo-EM) to examine the detailed structures of ...
Pain. Our least favorite thing. However, pain plays a vital role in our survival. It tells us when we’ve suffered an injury somewhere in the body, and it’s a warning to avoid certain situations or ...
Phase II Study of Lapatinib in Combination With Trastuzumab in Patients With Human Epidermal Growth Factor Receptor 2–Positive Metastatic Breast Cancer: Clinical Outcomes and Predictive Value of Early ...
In a new study evaluating meditation for chronic lower back pain, researchers at University of California San Diego School of Medicine have discovered that men and women utilize different biological ...
When you were a child and fell playing outside, a single bandage — a placebo of sorts — could take away the pain. The placebo effect has long been somewhat of a medical mystery. While researchers ...