In July 2022, the World Health Organization (WHO) announced that monkeypox was a public health emergency of international concern. And, as of early December 2022, more than 82,000 human monkeypox ...
A research team at the University of Würzburg has deciphered another aspect of poxviral gene activation. They have revealed a unique viral mechanism: A molecular ring anchors the viral copying machine ...
A computational model of the more than 26 million atoms in a DNA-packed viral capsid expands our understanding of virus structure and DNA dynamics, insights that could provide new research avenues and ...
Using cryo-microscopy, researchers present a high-resolution structure of monkeypox virus DNA polymerase holoenzyme, a complex that plays a key role in the genome replication process of the virus. The ...
Researchers identified how the poxvirus protein VITF-3 forms a molecular ring that clamps onto DNA with viral RNA polymerase, bending it by 90 degrees to initiate gene copying.
A giant virus discovered in Japan is adding fuel to the provocative idea that viruses helped create complex life. Named ushikuvirus, it infects amoebae and shows unique traits that connect different ...
Ancient viral fossils buried in our DNA are offering fresh clues about how today’s respiratory pathogens infect and spread. By tracing the shared architecture between long-extinct retroviruses and ...
The first atom-level model of a DNA-packed viral capsid reveals genome structure and possible new drug targets, University of Illinois researchers report. Pictured, from left: physics professor ...
A research team at the University of Würzburg has deciphered another aspect of poxviral gene activation. The study reveals a ...