The genetic information of all living cells is stored in the DNA composed of the four canonical bases adenine (A), cytosine (C), guanine (G) and thymine (T). An international team of researchers has ...

During the process of transcription, DNA is converted to RNA, a complex molecule that is able to carry genetic information outside of the cell's nucleus. This page guides you through the biochemical ...

Researchers at the Indian Institute of Science (IISc), with collaborators from the Institute of Mathematical Sciences (IMSc), ...

This image illustrates the chemical structures of the five main nucleobases found in DNA and RNA. The pyrimidines, thymine (DNA), uracil (RNA), and cytosine are shown on top while the purines, adenine ...

Figure 1: Stepwise evolution of DNA on the basis of what is inferred from modern biochemical pathways. Figure 4: 'Leaky' mismatch-specific uracil-DNA glycosylase as a driving force for evolution of ...

Researchers at The Ohio University have uncovered the mechanism by which thymine and guanine, the most commonly mutated bases in DNA, become damaged. The study, which was recently published in the ...

Researchers at the Indian Institute of Science (IISc), with collaborators from the Institute of Mathematical Sciences (IMSc), ...

Cytosine methylation at CpG dinucleotides produces m⁵CpG, an epigenetic modification that is important for transcriptional regulation and genomic stability in vertebrate cells. However, m⁵C ...

DNA is the molecular basis of heredity, the inherited traits that pass between generations in a person's family tree. Embodied in the sequence of base pairs, DNA carries information between ...

Exposure to ionizing radiation leads to formation of covalent crosslinks between DNA and proteins. The nature, extent and site of the modifications are not well understood due to the difficulty in ...