When cells proliferate, genomic DNA is precisely duplicated once per cell cycle. Abnormalities in this DNA replication process can cause alterations in genomic DNA, promoting cellular aging, cancer, ...

Treating inherited diseases is one of the greatest challenges in modern medicine. In the future, targeted gene corrections at ...

DNA methylation is a key epigenome component that helps dictate how genes are expressed, contributing to normal cell and tissue differentiation during development, as well as the process of biological ...

Every person alive carries between 0.5% and 1% of their genome from a hominin that has no name, no fossils, and no sequenced ...

Scientists uncovered DNA from two mysterious human ancestors hidden in modern genomes, revealing new clues about our evolutionary past.

The MCM helicase is broadly bound across the genome, and its phosphorylation is antagonistically regulated by the kinase DDK and the phosphatase RIF1–PP1. TRESLIN–MTBP recognises the phosphorylated ...