Researchers have discovered how cells activate a last-resort DNA repair system when severe damage strikes. When genetic ...

DNA Repair Pathways in Clinical Practice: Lessons From Pediatric Cancer Susceptibility Syndromes. If you have the appropriate software installed, you can download article citation data to the citation ...

A new study published in Science Translational Medicine by researchers at The University of Texas MD Anderson Cancer Center ...

In a new study, scientists at the Max Planck Institute for Evolutionary Anthropology in Leipzig analyzed the impact of more than 2,000 clinically approved drugs on DNA repair and CRISPR genome editing ...

The researchers focused on Fanconi anemia, a rare inherited disorder characterized by a failure to repair specific types of ...

An elegant collaboration between researchers in the UK's two core-funded Medical Research Council Research Institutes, the Laboratory of Medical Sciences (LMS) in London and the Laboratory of ...

Despite the significance of immune checkpoint inhibitors (ICIs) in solid tumor treatment, identifying ICI-sensitive populations remains a challenge. Mutations in DNA damage response (DDR) pathway ...

Rb1 loss may serve as a predictive biomarker to guide new targeted therapies for select breast cancers resistant to standard ...

New research reveals that triggering a cell’s DNA damage response could be a promising avenue for developing novel treatments against several rare but devastating viruses for which no antiviral ...

A new study published today in Science Translational Medicine by researchers at The University of Texas MD Anderson Cancer ...