Cytokines are a group of small molecule proteins or polypeptides that are synthesized, stimulated, or secreted by immune cells (including monocytes, macrophages, T cells, B cells, NK cells, etc.) and ...

Interleukin-36 (IL-36) cytokines, comprising agonists (IL-36α, IL-36β and IL-36γ) and the receptor antagonist IL-36Ra, represent a pivotal subset of the IL-1 family that orchestrates both innate and ...

Rheumatoid arthritis (RA) is a common autoimmune disease in which the immune system recognizes autoantigens on otherwise healthy joint tissues as foreign invaders, inducing a localized inflammatory ...

Cytokines are a diverse group of small proteins produced and released by various cells. These molecules play a crucial role in regulating the immune system, communicating with it to modulate the ...

Psoriasis, a chronic inflammatory skin condition characterized by dry and scaly skin lesions, affects about 7.5 million people in the United States. Psoriasis results from abnormal proliferation of ...

Cytokines are well-known players in the immune response, helping to control inflammation and coordinate the responses of other immune cells. However, a growing body of evidence suggests that some ...

Sanofi’s success co-developing a blockbuster drug based on blocking the signaling of interleukin 4 and interleukin 13 (IL-4 and IL-13) makes it an ideal partner to collaborate on inflammatory ...

Feeling sluggish, depressed, anxious, and having trouble concentrating while being sick might not just be due to physical weakness. Extensive reports from health professionals have pointed out that ...

In vitro studies pinpoint signaling pathways that could be potential targets in oral squamous cell carcinoma treatments.

Nanovials are emerging as an accessible platform for performing single-cell functional screening leveraging standard instrumentation, such as flow cytometers and microfluidic single-cell sequencing ...

Cytokines are a large group of bioactive small molecule proteins synthesized and secreted by immune and non-immune cells. There are various types of cytokines that belong to different families and ...