Using a new technique, long-read sequencing, that allows DNA to be analyzed in much greater detail than before, a team of Swedish clinicians and researchers has discovered an unexpected complexity in ...

An AI tool identifies cells that can shed light on the earliest origins of cancer through a game of molecular ‘laser tag’. The human body relies on precise genetic instructions to function, and cancer ...

Stefan Fröhling, M.D., and Hartmut Döhner, M.D. The cause of chromosomal abnormalities remains poorly understood. Studies of various types of leukemia have shown that certain environmental and ...

Human egg cells are often prone to chromosomal errors. As women age, the error rate increases sharply — and can contribute to infertility, pregnancy loss, and ...

An international research team coordinated by Dr. Oscar Molina and Dr. Pablo Menéndez, from the Josep Carreras Leukaemia Research Institute, identifies chromosomal abnormalities associated to relapse ...

Three RIKEN researchers have shed light on the cellular mechanisms underlying chromosomal abnormalities that can cause miscarriages and congenital disorders such as Down syndrome. These abnormalities ...

Synthetic human chromosomes may transform gene therapy by carrying large therapeutic genes without altering natural DNA. Here ...

Translocations, in genetics, happen when chromosomes break and the pieces attach to other chromosomes. This mixing of genetic material has important results. The resultant chromosomes are lacking in ...

More than two-thirds of early miscarriages seem to be due to abnormal chromosomes, the packages of DNA within all our cells, in the embryo or fetus. The remaining third are probably also largely due ...

Through their method, the researchers discovered that chromosomal abnormalities in aging eggs therefore result from a combination of failures, ranging from a drop in REC8 levels to the gradual ...