Research reveals that five DNA letters can switch chromatin between fluid and solid-like states, influencing gene ...

Over the past few decades, advances in hematology have illuminated how a delicate balance between stem cell self-renewal and differentiation sustains healthy blood formation. In myelodysplastic ...

DNA inside human cells is not just floating around freely. It is tightly wrapped around small proteins, forming a long chain.

A game-changining achievement in genome science has identified over 140,000 distinct DNA loops in our cells, providing chromosome fold resolution that is among the best ever created. In this ongoing ...

A team of researchers has generated one of the most detailed 3D maps of human chromosomes, cataloging over 140,000 DNA looping interactions.

One of the most detailed 3D maps of how the human chromosomes are organized and folded within a cell's nucleus is published ...

It's a common storytelling trope: the stubborn foe who is eventually revealed to be a much-needed friend. Biology has its own ...

CTCF is widely recognized for its essential role in mediating chromatin loops to regulate gene expression, particularly by modulating enhancer-promoter (EP) interactions. However, acute depletion of ...