Ten years ago, three research teams published a breakthrough — the first description of the molecular mechanism for transduction in fingertip sensory Merkel cells that can transduce gentle touch, a ...
The gray portion of this schematic represents a nanodisc, where for the first time researchers were able to replicate the native membrane environment (red dots) of a T-cell receptor (cyan). One of the ...
Cells typically contain a cytoskeleton, which helps shuttle things around and provides structural integrity, among other functions. Microtubules are important parts of the cytoskeleton, and new ...
New research combines two powerful imaging techniques to study the complete structure of a common aGPCR, including how its long and complex extracellular region interacts with the transmembrane region ...
This new technique for studying cell receptors could have sweeping implications for drug development
Researchers created a tool capable of comprehensively mapping crucial interactions underlying drug efficacy in one superfamily of cell receptors. One in every three FDA-approved drugs targets a single ...
Scientists at École Polytechnique Fédérale Lausanne (EPFL), and at UNIL-CHUV, University Hospital Lausanne (CHUV) and University of Lausanne (UNIL) have developed a computational method to create ...
A new study explores the connection between obesity and Alzheimer's disease. Researchers found different cellular messengers in people with obesity that signal plaque formation in the brain. Here's ...
BIRMINGHAM, Ala. – Transduction is the changing of one form of energy into another, such as a spoken voice changed into radio waves by a cellphone. Ten years ago, three research teams published a ...
One of the most exciting advances in cancer treatments in the past decade is the development of T cell immunotherapies, in which a patient's own immune system is trained to recognize and attack ...
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