Autoantibodies that bind with high affinity to proteins of the complement system have been described in patients with systemic lupus erythematosus (SLE), the prototypic systemic autoimmune disease.
The defence collagens C1q and mannose-binding lectin (MBL) are immune recognition proteins that associate with the serine proteinases C1r/C1s and MBL-associated serine proteases (MASPs) to trigger ...
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