We have identified a macrophage population "Mrep" that plays an essential role in muscle repair. However, in Fibrodysplasia ossificans progressiva (FOP), Mrep functions as a pathogenic cell that ...

Researchers in Sweden have engineered a cell-free cartilage scaffold that can guide the body to rebuild damaged bone. By removing the cells but preserving the structure and natural growth signals, the ...

Cell- and animal-based models of bone formation reveal novel mechanisms involved in the cartilage-to-bone phenotype ...

Musculoskeletal disorders are a primary cause of disability worldwide, especially in aging societies like Japan. As individuals age, reductions in muscle mass and physical activity weaken the body's ...

A bone-like composite developed at EPFL uses naturally occurring enzymes to accelerate mineralization through an ...

Bones broken in a skiing accident usually heal on their own. But if the break is too severe or a bone tumor needs to be removed, surgeons insert an implant that enables the bone to grow back together.

A cube of healthy bone is anything but solid. Inside it, countless tiny channels carry fluid and help cells move, feed, and rebuild.

A novel hydrogel bone implant mimics natural healing via a fibrin network, featuring world-record printing speeds and ...

The first comprehensive single-cell atlas of bone-innervating sensory neurons has identified their dual role in reporting and repairing bone damage, providing a potential target for drugs that might ...