Here we present HiC-DC, a principled method to estimate the statistical significance (P values) of chromatin interactions from Hi-C experiments. HiC-DC uses hurdle negative binomial regression account ...
In this article, we propose a generalized Gaussian process concurrent regression model for functional data, where the functional response variable has a binomial. Poisson, or other non-Gaussian ...
We derive a first-order bias-corrected maximum likelihood estimator for the negative binomial dispersion parameter. This estimator is compared, in terms of bias and efficiency, with the maximum ...