Reuters

Bile acid-binding resin treats diabetes, in mice

NEW YORK (Reuters Health) - Colestimide, a resin that binds and eliminates bile acids, seems to be an effective treatment for obesity and type 2 diabetes -- at least in mice -- according to a report ...
Seeking Alpha

Intercept Announces FDA Acceptance of Supplemental New Drug Application for Ocaliva® (obeticholic acid) for the Treatment of PBC

sNDA intended to satisfy post-marketing requirements to confirm a clinical benefit in patients with PBC Precedent-setting submission includes data from post-marketing studies COBALT and Study 401 as ...
Nasdaq

Intercept Announces Closing of Transaction with Advanz Pharma to Transfer Rights to Commercialize Ocaliva® for PBC Outside the U.S.

MORRISTOWN, N.J., July 01, 2022 (GLOBE NEWSWIRE) -- Intercept Pharmaceuticals, Inc. (Nasdaq:ICPT), a biopharmaceutical company focused on the development and commercialization of novel therapeutics to ...
Nasdaq

Bylvay® (odevixibat) data shows sustained improvement in severe itch and serum bile acid levels in patients with PFIC and ALGS

PARIS, FRANCE, 18 November, 2024 Ipsen (Euronext: IPN; ADR: IPSEY) today announced data at the American Association for the Study of Liver Diseases (AASLD) assessing the long-term efficacy and safety ...
MarketWatch

Intercept Announces Voluntary Withdrawal of OCALIVA(R) for Primary Biliary Cholangitis (PBC) from the US Market; US Clinical Trials Involving Obeticholic Acid Placed on ...

The MarketWatch News Department was not involved in the creation of this content. MORRISTOWN, N.J., Sept. 11, 2025 (GLOBE NEWSWIRE) -- Intercept Pharmaceuticals, Inc., a wholly owned biopharmaceutical ...
Seeking Alpha

Travere Therapeutics Enters Agreement to Sell its Bile Acid Product Portfolio for the Treatment of Rare Liver Diseases to Mirum Pharmaceuticals | Seeking Alpha

• Travere to receive up to $445 million with $210 million upfront and up to $235 million in potential sales-based milestones • Advances Travere’s strategy to deliver new treatment standards from its ...
The American Journal of Managed Care

Alternatives to Add-On Therapy for T2D and Hyperlipidemia

Zachary T. Bloomgarden, MD, MACE: There’s a misconception that fibrates, as a class, are associated with adverse muscle reactions to statins. In fact, this is absolutely a finding with gemfibrozil.
EurekAlert!

Bile acid transport in the enterohepatic circulation. (IMAGE)

In hepatocytes, bile acids are secreted into bile canaliculi by bile salt export pump (BSEP), cholesterol is secreted by ATP binding cassette subfamily G member 5 (ABCG5) and ABCG8 heterodimer and ...