Bacterial gene regulation is a finely tuned process essential for cellular adaptation and survival. Central to this regulation are nucleoid-associated proteins (NAPs), which not only compact the ...
Researchers turned programmable proteins into a novel genetic tool, potentially enabling tighter control of gene expression. LacI is a tetrameric protein, using two dimers to bind two specific, ...
Engineered oncolytic bacteria have emerged as a promising therapeutic platform for precision cancer treatment, offering tumor-specific colonization, immune activation, and controllable therapeutic ...
Scientists studying thousands of rats discovered that gut bacteria are shaped by both personal genetics and the genetics of ...
Proceedings of the National Academy of Sciences of the United States of America, Vol. 119, No. 40 (October 4, 2022), pp. 1-9 (9 pages) Horizontal gene transfer drives bacterial evolution. To confer ...
If something similar occurs in humans, and given growing evidence that the gut microbiome matters for health, genetic ...
Given the growing antibiotic resistance crisis, novel ways to target bacterial infections are becoming increasingly important. One potential strategy is to manipulate bacterial genes at the ...
Your "roommate's" genes could be influencing the bacteria living in your gut, and vice versa, according to a study of rats ...
Epigenome editing has followed a similar path, in that more recent technological breakthroughs have enabled scientists to apply the discoveries made in previous decades. Epigenome editing performs a ...
Everyday substances, including caffeine, can trigger changes in bacteria like E. coli that make antibiotics less effective. Caffeine activates a regulatory path involving a bacterial protein called ...
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