Caspases are a family of proteolytic enzymes that play a central role in apoptosis, the regulated process of programmed cell death essential for development, homeostasis and the clearance of damaged ...

In animals the process of programmed cell death, or apoptosis, is thought to be mediated by caspases, a family of cysteine proteases that cleave one another and key intracellular proteins, killing the ...

Caspase Related Reagents Courtesy of Bingren Hu, Queen's Medical Center, Hawaii. Provided by Cell Signaling TechnologyConfocal micrograph of double immunostaining for cleaved caspase-3 (green) and ...

Apoptosis, or programmed cell death, is a tightly regulated biological process necessary for normal tissue maintenance and development. However, aberrations in apoptotic signaling networks are ...

Researchers have identified a previously unknown inflammatory mechanism that may drive the aggressiveness and relapse of small cell lung cancer. Small cell lung cancer (SCLC) is among the most ...

Like a phoenix rising from the ashes, our skin tissue—and in fact many types of epithelial tissue that lines and covers the body's organs—can respond to death and destruction with a burst of ...