Aneuploidy is extraordinarily common in humans, occurring in an estimated 20–40% of all conceptions. It is the most common cause of miscarriages and congenital defects in our species and is a leading ...
Cancer cells with extra chromosomes depend on those chromosomes for tumor growth, a new Yale study reveals, and eliminating them prevents the cells from forming tumors. The findings, said the ...
Assessing tumor-infiltrating immune cells and outcomes with cisplatin- versus carboplatin-based treatment in advanced urothelial cancer (UC): Survival analysis of three platinum-treated UC cohorts.
Rajiv McCoy is a co-inventor on a provisional patent related to this work, filed with the United States Patent and Trademark Office (USSN 62/080,251) by Stanford University on Nov. 14, 2014. He has ...
Traditionally, aneuploidy was diagnosed by counting the metaphase chromosomes under the microscope. However, in many cases, and primarily due to the high or lower number of chromosomes, it was ...
Yale scientists have discovered a new potential treatment avenue to fight cancer. Using CRISPR gene-editing, the team eliminated extra chromosomes from cancer cells and found that they could no longer ...
Women hear the loaded reminders far too often: if you want to have children, you’d better do it before it’s too late. But why is it that eggs get less fertile as time passes? “Even if a woman is still ...
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