The amide bond can be activated for cleavage under mild, neutral conditions by chemical derivatization, a British group has demonstrated (Angew. Chem. Int. Ed., DOI: 10.1002/anie.201107117). Amide ...

With its simple bicyclic skeleton, 2-quinuclidone doesn't look like it would be much of a challenge to make. But thanks to an unusually labile amide linkage, this modest lactam has eluded synthetic ...

In proteins, amino acids are held together by amide bonds. These bonds are long-lived and are robust against changes in temperature, acidity, or alkalinity. Certain medicines make use of reactions ...

In proteins, amino acids are held together by amide bonds. These bonds are long-lived and are robust against changes in temperature, acidity or alkalinity. Certain medicines make use of reactions ...

This is a scheme of reaction rate acceleration of amide hydrolysis by inclusion in the self-assembled molecular cage. Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news ...