The Scientist

Affinity versus Avidity: Differentiating Between Binding Phenomena

To choose the best lead candidates during drug and antibody screening, scientists characterize a molecule’s binding properties, such as kinetics and affinity. Robust assay design reduces experimental ...
Medscape

Intravenous Immunoglobulin IgG Response Associated with Poor Outcome in Guillain-Barré Syndrome

Guillain-Barré syndrome (GBS) is an acute inflammatory neuropathy that can lead to severe weakness of the limbs, face, and respiratory muscles. Its pathophysiology involves autoantibodies that attack ...
Business Wire

Cyrus Biotechnology Announces Potent in vivo Redosability of an Engineered IdeS Protease for IgG-driven Autoimmune Disease, Demonstrating No Anti-drug Antibodies

IdeS IgG protease shows promise for Myasthenia Gravis, Immune Thrombocytopenia, and dozens of other IgG-driven autoimmune diseases. The wild type enzyme elicits potent anti-drug antibodies (ADA) that ...
News Medical

Immunoglobulin G isotypes switch class following repeated SARS-CoV-2 mRNA vaccination

In a recent study posted to the medRxiv* preprint server, researchers reported a class switch in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-specific antibodies due to repeated ...