Nicotine addiction remains one of the most persistent public health challenges worldwide, driven by changes in the brain that reinforce repeated use and make quitting extremely difficult. For decades, ...

University of Oregon neuroscientists have identified a group of brain cells that essentially act as a "disappointment meter," ...

Scientists say they've uncovered striking new evidence of how alcohol addiction impacts the brain's learning systems—and how those systems may slowly adapt during recovery—in a new study published in ...

Participants took 25mg of psilocybin, reporting deeper psychological insight and better wellbeing a month later ...

For decades, my colleagues and I advanced the premise that early substance use—nicotine, alcohol, or cannabis (or other addicting drugs)—interferes with critical maturation stages, particularly ...

Addiction is one of the most common and consequential chronic medical conditions in the United States. Nationwide, more than 46 million people met the criteria for a substance abuse disorder as of ...

New research discovers a lateral habenula cell group acting as a disappointment meter when reality misses expectations.