A comprehensive mini-review published today after peer review in Brain Medicine by Dr. Tao Ma and colleagues at Wake Forest ...

Nimbus Therapeutics announced it has entered into a multi-year research collaboration and $1.3 exclusive license agreement ...

Lilly has seen dramatic sales growth over the last couple of years from its injectable, dual GLP-1/GIP agonist obesity ...

Nimbus and Eli Lilly collaborate to develop an oral treatment for obesity, leveraging computational chemistry and structure-based drug design. Nimbus Therapeutics and Eli Lilly announce their ...

Adenosine monophosphate (AMP)-activated protein kinase (AMPK) plays an important role in cellular energy homeostasis, helping in growth regulation and metabolic reprogramming in eukaryotes. The AMPK ...

Caffeine appears to do more than perk you up—it activates AMPK, a key cellular fuel sensor that helps cells cope with stress and energy shortages. This could explain why coffee is linked to better ...

The AMP-activated protein kinase (AMPK) system was discovered in mammalian cell extracts as activities that phosphorylated and inactivated key enzymes of lipid biosynthesis, that is, acetyl-CoA ...

Coffee has been linked to longevity in past studies, with some suggesting that 3 cups is the magic number for living longer. A new study published in Microbial Cell found that the caffeine in coffee ...

AMP-activated protein kinase (AMPK) is a highly conserved sensor of low intracellular ATP levels that is rapidly activated after nearly all mitochondrial stresses, even those that do not disrupt the ...

Researchers have developed a new system that lets them study in more detail than ever exactly how, where and when the metabolic protein AMPK carries out its molecular and therapeutic functions. The ...