Joe Biden is set to begin his long-anticipated maiden visit to Africa as US president but it comes amidst uncertainty over future US-Africa relations as Donald Trump prepares to succeed him in January.

The president will also announce initiatives related to global health and security cooperation, among other things, a senior administration official said.

President Biden will travel to Angola this week, becoming the first sitting president to do so and following through on a years-long pledge to visit sub-Saharan Africa.